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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MUSK
All Species:
21.52
Human Site:
S677
Identified Species:
39.44
UniProt:
O15146
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15146
NP_005583.1
869
97056
S677
M
S
P
H
T
V
C
S
L
S
H
S
D
L
S
Chimpanzee
Pan troglodytes
Q5IS37
825
92786
G633
N
K
F
L
R
A
H
G
P
D
A
M
I
L
V
Rhesus Macaque
Macaca mulatta
XP_001106626
869
96940
S677
M
S
P
H
T
V
C
S
L
S
H
S
D
L
S
Dog
Lupus familis
XP_538784
992
109405
R677
R
S
P
H
A
A
P
R
S
P
G
P
P
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q61006
868
96674
S676
M
S
P
H
T
V
C
S
L
S
H
S
D
L
S
Rat
Rattus norvegicus
Q62838
868
96804
S676
M
S
P
H
T
V
C
S
L
S
H
S
D
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508938
874
97520
S682
M
S
P
R
T
V
C
S
L
S
H
G
N
L
V
Chicken
Gallus gallus
Q8AXY6
947
105570
S757
R
S
P
R
N
L
C
S
L
V
Q
G
G
L
E
Frog
Xenopus laevis
Q9PVZ4
1362
153727
M1092
G
Q
P
T
L
V
I
M
E
L
M
A
H
G
D
Zebra Danio
Brachydanio rerio
NP_001004503
941
106241
S748
R
C
A
T
Q
Q
P
S
L
S
R
D
T
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6K3
724
81818
A540
L
R
A
C
S
P
Y
A
T
H
Q
A
P
T
Q
Honey Bee
Apis mellifera
XP_391863
648
74770
S465
K
D
E
H
F
T
D
S
R
L
S
H
M
D
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q26614
972
110463
V720
E
G
P
P
Y
V
I
V
E
F
A
H
H
G
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.7
99.1
80.9
N.A.
93
93.4
N.A.
82.7
71.3
20.1
59
N.A.
29.9
33.5
N.A.
22.5
Protein Similarity:
100
42.9
99.5
82.5
N.A.
96.4
96.8
N.A.
90.2
80.9
35.5
70.7
N.A.
44.9
48.3
N.A.
40
P-Site Identity:
100
6.6
100
20
N.A.
100
100
N.A.
73.3
40
13.3
26.6
N.A.
0
13.3
N.A.
13.3
P-Site Similarity:
100
6.6
100
26.6
N.A.
100
100
N.A.
80
46.6
20
33.3
N.A.
26.6
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
8
16
0
8
0
0
16
16
0
0
8
% A
% Cys:
0
8
0
8
0
0
47
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
8
0
0
8
0
8
31
8
8
% D
% Glu:
8
0
8
0
0
0
0
0
16
0
0
0
0
0
8
% E
% Phe:
0
0
8
0
8
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
8
8
0
0
0
0
0
8
0
0
8
16
8
16
0
% G
% His:
0
0
0
47
0
0
8
0
0
8
39
16
16
0
0
% H
% Ile:
0
0
0
0
0
0
16
0
0
0
0
0
8
0
0
% I
% Lys:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
8
8
8
0
0
54
16
0
0
0
62
8
% L
% Met:
39
0
0
0
0
0
0
8
0
0
8
8
8
0
0
% M
% Asn:
8
0
0
0
8
0
0
0
0
0
0
0
8
0
8
% N
% Pro:
0
0
70
8
0
8
16
0
8
8
0
8
16
8
0
% P
% Gln:
0
8
0
0
8
8
0
0
0
0
16
0
0
0
8
% Q
% Arg:
24
8
0
16
8
0
0
8
8
0
8
0
0
0
0
% R
% Ser:
0
54
0
0
8
0
0
62
8
47
8
31
0
0
31
% S
% Thr:
0
0
0
16
39
8
0
0
8
0
0
0
8
8
8
% T
% Val:
0
0
0
0
0
54
0
8
0
8
0
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _